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Why study proteins in the fish lens?

Analysis of zebrafish
lens proteins

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Role of crystallins in
lens development

My lab investigates the evolution and biological role of lens proteins called crystallins. These proteins are responsible for making the lens transparent and refracting light so that focused images fall on the retina. Amazingly, one family of crystallins, the alpha crystallins, also protect other proteins from the harmful effects of aging that can lead to lens cataracts, one of the leading causes of blindness in humans.

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Alpha crystallin chaperone function

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Lab Members